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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR7
All Species:
31.82
Human Site:
Y574
Identified Species:
58.33
UniProt:
Q9Y4E6
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4E6
NP_056100.2
1490
163810
Y574
K
W
R
P
S
D
D
Y
L
V
V
G
C
S
D
Chimpanzee
Pan troglodytes
XP_523934
1490
163873
Y574
K
W
R
P
S
D
D
Y
L
V
V
G
C
S
D
Rhesus Macaque
Macaca mulatta
XP_001084761
1490
163815
Y574
K
W
R
P
S
D
D
Y
L
V
V
G
C
S
D
Dog
Lupus familis
XP_533395
1491
164172
Y575
K
W
R
P
S
D
D
Y
L
V
V
G
C
S
D
Cat
Felis silvestris
Mouse
Mus musculus
Q920I9
1489
163386
Y574
K
W
R
P
S
D
D
Y
L
V
V
G
C
T
D
Rat
Rattus norvegicus
Q9ERH3
1488
163172
Y574
K
W
R
P
S
D
D
Y
L
V
V
G
C
T
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510427
1487
163542
Y574
K
W
R
P
S
D
D
Y
L
V
V
G
C
S
D
Chicken
Gallus gallus
XP_001231557
1487
163610
Y574
K
W
R
P
S
D
D
Y
L
V
V
G
C
S
D
Frog
Xenopus laevis
NP_001085633
956
105584
M164
S
P
D
W
I
S
S
M
S
I
I
R
S
H
R
Zebra Danio
Brachydanio rerio
XP_701317
1059
116678
A267
W
A
G
G
E
F
I
A
A
D
K
V
I
I
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569960
1525
168458
F571
K
W
R
P
L
D
D
F
L
I
V
G
C
S
D
Honey Bee
Apis mellifera
XP_395749
1488
164925
F575
K
W
R
P
L
D
D
F
M
I
V
G
C
S
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784047
1449
158495
F579
K
W
R
P
A
E
D
F
L
I
V
G
L
E
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99.2
96.9
N.A.
94.9
94.5
N.A.
93.3
90.4
55.7
57.3
N.A.
41.9
45.5
N.A.
47.2
Protein Similarity:
100
99.7
99.7
98.4
N.A.
97.3
97.1
N.A.
96.4
95.3
60.4
64.3
N.A.
61.6
65.2
N.A.
66.1
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
100
100
0
0
N.A.
80
73.3
N.A.
60
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
13.3
0
N.A.
93.3
93.3
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
0
0
8
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
77
0
0
% C
% Asp:
0
0
8
0
0
77
85
0
0
8
0
0
0
0
85
% D
% Glu:
0
0
0
0
8
8
0
0
0
0
0
0
0
8
0
% E
% Phe:
0
0
0
0
0
8
0
24
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
8
0
0
0
0
0
0
0
85
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
8
0
8
0
0
31
8
0
8
8
0
% I
% Lys:
85
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% K
% Leu:
0
0
0
0
16
0
0
0
77
0
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
8
0
85
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
85
0
0
0
0
0
0
0
0
8
0
0
8
% R
% Ser:
8
0
0
0
62
8
8
0
8
0
0
0
8
62
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
16
0
% T
% Val:
0
0
0
0
0
0
0
0
0
62
85
8
0
0
0
% V
% Trp:
8
85
0
8
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
62
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _